Arthur Clifton Guyton (September 8, 1919 – April 3, 2003) was an American physiologist best known for his studies on cardiovascular physiology and his ''Textbook of Medical Physiology'', which quickly became the standard text on the subject in medical schools. The first edition was published in 1956, the 10th edition in 2000 (the last before Guyton's death), and the 12th edition in 2010. The 14th edition published in 2020 is the latest version available. It is the world's best-selling medical physiology textbook.
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